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CLINICAL PIPELINE

Pain Therapeutics is a biopharmaceutical company that develops novel drugs for pain management and hematology/oncology. We have three investigational drug candidates in clinical programs. Remoxy™ and PTI-202 are proprietary, abuse-deterrent forms of opioid drugs. Oxytrex™ is a novel, next-generation painkiller that potentially offers less physical dependence than currently marketed opioid painkillers. Our early-stage drugs include a novel radio-labeled monoclonal antibody to treat metastatic melanoma, a deadly form of skin cancer. We are also working on a new treatment for patients with hemophilia, a rare blood disorder. The FDA has not yet evaluated the merits, safety or efficacy of our drug candidates.

PIPELINE STATUS

Drug Candidate Indication Phase Commercial Rights
Remoxy Moderate/severe chronic pain III King Pharmaceuticals
Oxytrex Moderate/severe chronic pain III Pain Therapeutics, Inc.
PTI-202 Moderate/severe chronic pain I King Pharmaceuticals
Monoclonal Antibody Metastatic melanoma I Pain Therapeutics, Inc.
Factor IX Replacement Hemophilia Pre-clinical Pain Therapeutics, Inc.

Note: Our drug candidates are in development stages and have not yet been apporved by the U.S. Food and Drug Administration.